The Forest, divided into two separate units, is located in the southeastern portion of the state. Its southern boundary begins only 5 miles north of the Gulfport-Biloxi area. Hattiesburg is located between the two units, and Laurel is just 10 miles north of the northern boundary. The numerous major travel routes include US Highways 49 and 98, State Highways 67, 15, 57, 26, 29, 13, 63, and 42.

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